Thiazole compounds
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United States of America Patent
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Apr 3, 2001
Grant Date -
N/A
app pub date -
Jun 1, 1998
filing date -
Dec 1, 1995
priority date (Note) -
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Abstract
The invention relates to a process for preparing a compound of formula (I), in which X is CH or N, Y is NO.sub.2 or CN, Z is CHR.sub.3, O, NR.sub.3 or S, R.sub.1 and R.sub.2 are either each, independently of the other, hydrogen or unsubstituted or R.sub.4 -substituted alkyl or together a two-or three-membered alkylene bridge or a two- or three-membered alkylene bridge in which one member is replaced by a hetero member selected from the group, consisting of NR.sub.5, O and S, R.sub.3 is H or unsubstituted or R.sub.4 -substituted alkyl, R.sub.4 is an unsubstituted or substituted aryl or heteroaryl group, and R.sub.5 is H or alkyl, which comprises a) reacting a compound of formula (II) with a chlorinating agent or b1) initially reacting a compound of formula (IV) with a compound of formula (V) and b2) further reacting the compound of formula (II) obtainable thereby, with or without intermediate isolation, with a chlorinating agent, to intermediates used in this process, to the use of these intermediates and to a process for the preparation of these intermediates.
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