Regioselective synthesis of DTPA derivatives
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United States of America Patent
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Mar 27, 2001
Grant Date -
N/A
app pub date -
Mar 3, 1999
filing date -
Mar 3, 1999
priority date (Note) -
Expired
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Abstract
The present invention provides a process for high yield regioselective synthesis of DTPA derivatives that eliminates the need for ion exchange chromotographic separation of intermediates. Moreover, as this process yields a single regioisomer of the chelate, it provides for the regiospecific synthesis of desired chelates useful as radiolabeling agents.
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