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United States of America Patent
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Mar 20, 2001
Grant Date -
N/A
app pub date -
May 7, 1993
filing date -
Sep 7, 1990
priority date (Note) -
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Abstract
A reshaped human antibody or reshaped human antibody fragment having specificity for human polymorphic epithelial mucin (PEM) is produced by transferring the complementarity determining regions (CDRS) from a murine anti-HMFG hybridoma cell line HMFG1 into a human antibody variable region framework. The reshaped molecule can be used in the treatment or diagnosis of cancer.
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