Method for determining the immunocompetence of a mammal and therapies related thereto
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Mar 6, 2001
Grant Date -
N/A
app pub date -
Jan 21, 1998
filing date -
Jan 22, 1997
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A method for determining the immunocompetence of a mammal is described. Bodily fluid having T cell receptor complexes from a mammal is provided. Expression of a first component and a second component of the T cell receptor complexes is evaluated. An abnormal ratio of the number of cells expressing the first component as compared to the number of cells expressing the second component indicates altered immunocompetence in the mammal. Also described are methods for monitoring a therapeutic treatment of a disease in a mammal associated with an abnormal level of a T cell receptor complex component, methods for assessing the progression of a disease in a mammal associated with an abnormal level of a T cell receptor complex component, methods for predicting the prognosis of a mammal having a disease associated with an abnormal level of a T cell receptor complex component, methods for determining if a mammal is at risk for AIDS, methods for evaluating an agent for use in treating HIV infection, and methods for treating HIV infection in a mammal. Pharmaceutical compositions and kits are also provided.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully