Engineered acarid allergen and process for producing the same
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United States of America Patent
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Feb 13, 2001
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N/A
app pub date -
Sep 26, 1997
filing date -
Mar 28, 1995
priority date (Note) -
Expired
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Abstract
The invention provides a method for producing a modified major mite allergen, obtained by altering a major allergen of house dust mites by gene engineering, which involve the steps of culturing prokaryotic or eukaryotic host cells transformed with a replication vector containing a gene encoding modified major mite allergen expressed from a promoter and collecting the expressed modified major mite allergen from the culture. The present invention provides a modified major mite allergen produced by the method, DNA molecules encoding same, and a pharmaceutical composition containing the modified major mite allergen.
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