N-hydroxyurea derivative and pharmaceutical composition containing the same
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United States of America Patent
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-
Feb 6, 2001
Grant Date -
N/A
app pub date -
Jun 23, 1999
filing date -
Dec 26, 1996
priority date (Note) -
Expired
status (Latency Note)
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Abstract
An N-hydroxyurea derivative having an antiallergic action or anti-inflammatory action having the formula ##STR1## wherein, either one of R.sub.1, R.sub.3, and R.sub.4 represents A, either one of the other groups of R.sub.1, R.sub.3, and R.sub.4 and R.sub.2 represents a 3-pyridyl group or 3-pyridylalkyl group, the remaining groups of R.sub.1, R.sub.2, R.sub.3, and R.sub.4 independently represent a hydrogen atom, halogen atom, or a substituted or unsubstituted C.sub.1 to C.sub.8 alkyl group, R.sub.5 represents a hydrogen atom or lower alkyl group, R.sub.6 represents a hydrogen atom, lower alkyl group, C.sub.3 to C.sub.7 cycloalkyl group, or a substituted or unsubstituted phenyl group, where the substituent represents a halogen atom, lower alkyl group, or lower alkoxy group, B represents a bond, C.sub.1 to C.sub.20 alkylene group, C.sub.2 to C.sub.8 alkenylene group, or C.sub.2 to C.sub.8 alkynylene group or B--C(R.sub.5) represents a C.sub.2 to C.sub.6 alkylene group having a benzene ring in the middle thereof or its pharmacologically acceptable salt or the hydrate or solvate thereof.
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