Process for the preparation of 1,4,7,10-tetraaza-cyclododecane-1,4,7-triacetic acid and the derivatives thereof

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United States of America Patent

PATENT NO 6166201
SERIAL NO

09524751

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A process for the preparation of 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid and the salts thereof of formula (I) ##STR1## which comprises the following steps: a) carboxymethylation reaction of a suitable precursor in water, with a haloacetic acid, b) hydrolysis reaction in basic conditions by addition of the base added at the previous step.

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BRACCO INTERNATIONAL B V1077 ZX AMSTERDAM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ausonio, Marina Milan, IT 12 34
Murru, Marcella Milan, IT 14 61
Panetta, Emanuela Milan, IT 4 13
Ripa, Giorgio Milan, IT 25 78
Scala, Alessandro Milan, IT 10 38
Viscardi, Carlo Felice Milan, IT 23 63

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