Bone marrow cultures for developing suppressor and stimulator cells for research and therapeutic applications
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United States of America Patent
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Dec 26, 2000
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Oct 23, 1998
filing date -
May 24, 1996
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Abstract
A method of treatment using immune system suppressor cells and immune system stimulator cells comprises providing stem cells; combining the stem cells with lymphoid-derived cells to produce a co-culture; adding lipopolysaccharide and a factor selected from the group consisting of granulocyte macrophage-colony stimulating factor, macrophage colony stimulating factor, granulocyte-colony stimulating factor and mixtures thereof to the co-culture; obtaining immune system suppressor cells and immune system stimulator cells from the co-culture; and introducing and the cells into a host.
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