Agent for dehydrating corneas in organ culture

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United States of America Patent

PATENT NO 6162642
SERIAL NO

09359374

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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An agent for dehydrating corneas, in particular eye corneas for organ culture, contains the culture medium and as dehydrating substance hydroxyethylstarch with a mean molecular weight Mw from 070,000 to 200,000, an MS substitution degree from 0.15 to 0.5, a DS substitution degree from 0.15 to 0.5 and a C2-C6 substitution ratio at the anhydroglucose units .ltoreq.8. The dehydrating substance is preferably hydroxyethylstarch with a mean molecular weight Mw 130,000.+-.20,000, an MS substitution degree from 0.38 to 0.45, a DS substitution degree from 0.32 to 0.40 and a C2-C6 substitution ratio at the anhydroglucose units from 8 to 20. The hydroxyethylstarch is used in a concentration from 1 to 20 (weight/vol.) %, preferably from 2 to 15 (weight/vol.) %, and in particular of 7.5% (weight/vol.). Also disclosed is the use of this hydroxyethylstarch as a dehydrating substance for the organ culture of corneas, in particular eye corneas, and the use of this hydroxyethylstarch for preparing a dehydrating agent for corneas, in particular eye corneas for organ culture.

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Patent Owner(s)

Patent OwnerAddress
FRESENIUS AGELSE-KRONER-STRASSE 1 D-61352 BAD HOMBURG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Redbrake-Adams, Claudia Aachen, DE 1 6
Reim, Martin Aachen, DE 1 6

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