Composition containing an acid-labile benzimidazole and process for its preparation
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United States of America Patent
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Dec 12, 2000
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N/A
app pub date -
Oct 20, 1998
filing date -
Sep 21, 1995
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Abstract
The present invention relates to a composition, particularly adapted to oral administration, substantially free of alkaline-reacting compounds. The composition comprises (a) a core containing an acid-labile benzimidazole active principle, where the core comprises a plurality of nuclei and the active principle mixed together and then compressed together, and where the active principle is not in the form of an alkaline salt; (b) an intermediate layer; and (c) an enteric layer; provided that omeprazole is not the benzimidazole active principle. A process for preparing the composition is also disclosed.
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