Method for the low-waste manufacture of diskoid moulded bodies containing active ingredients, and transdermal therapeutic systems containing same

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United States of America Patent

PATENT NO 6156336
SERIAL NO

09308428

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Abstract

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Active ingredient-containing layered articles or discs which are suitable, in particular, as active ingredient reservoirs for transdermal therapeutic systems are obtained starting from an elongate article having an enveloping surface corresponding to the contour of the layered articles to be produced, and having a cross-sectional constitution corresponding to the internal structure of the layered articles, by layered detachment perpendicular to the axial direction of the elongate article. In the simplest case, this article consists of a uniform active ingredient-containing composition and forms a solid cylinder which is converted into single products perpendicular to the axis with identical spacing to result in circular one-compartment discs identical to one another. The article can, however, have any other external shape and internal structure, in particular be formed by a consolidated bundle of strands with different active ingredients or active ingredient concentrations and be converted into single discs with a plurality of compartments in one plane. Suitable 'active ingredients' are not only medicinal substances and their precursors and activators, but also any reagents, auxiliaries, test substances etc.

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Patent Owner(s)

Patent OwnerAddress
LTS LOHMANN THERAPIE-SYSTEME GMBH56567 NEUWIED

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bracht, Stefan Ochtendung, DE 36 782

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