Soluble prodrugs of paclitaxel
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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-
Nov 28, 2000
Grant Date -
N/A
app pub date -
Jun 3, 1997
filing date -
Jun 4, 1996
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Novel 2'-onium salts of paclitaxel act as prodrugs in mammalian patients to yield paclitaxel in vivo. Methods of synthesizing these onium salts are disclosed, as are methods of treating patients suffering from paclitaxel-responsive diseases by administering effective amounts of the onium salts and pharmaceutical compositions containing the novel salts which are suitable for administration to patients requiring paclitaxel therapy.
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