Method for analyzing a polynucleotide containing a variable sequence
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United States of America Patent
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Nov 21, 2000
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app pub date -
Oct 6, 1997
filing date -
Apr 7, 1995
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Abstract
A method of analyzing a polynucleotide target involves incubating the target with an oligonucleotide probe, generally an array of immobilised oligonucleotide probes, to form a duplex, and using ligase or polymerase to extend one chain of the duplex. A point mutation or variable number tandem repeat section may be analysed. Arrays of immobilised oligonucleotides are provided for use in the method.
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