Sandwich immunoassays for collagen type II degradation products

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United States of America Patent

PATENT NO 6143511
SERIAL NO

09457440

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Abstract

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Sandwich immunoassays for detecting analyte indicative of type II collagen resorption in vivo, by contacting a body fluid sample with a first antibody and a second antibody such that analyte present in the sample forms a first antibody-analyte-second antibody complex, and detecting the presence or amount of the first antibody-analyte-second antibody complex, wherein the first and second antibodies are capable of binding to a telopeptide having a sequence identical to that of a carboxy-terminal telopeptide produced in vivo upon degradation of type II collagen.

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Patent Owner(s)

Patent OwnerAddress
WASHINGTON RESEARCH FOUNDATIONSEATTLE WASHINGTON 98102

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Eyre, David R Mercer Island, WA 44 556

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