Taxoid compound and method for producing the same

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United States of America Patent

PATENT NO 6136990
SERIAL NO

09504788

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Abstract

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A taxoid compound represented by general formula (I) ##STR1## where the symbols R.sup.1, R.sup.2, R.sup.3, R.sup.4, Bz, and Ac have specified meanings. Also, a method for producing the taxoid derivative from a baccatin derivative having a .beta.-ketoester group at the 13-position by transesterification and a method for producing taxoid compound such as paclitaxel from the taxoid derivative under mild condition are disclosed.

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Patent Owner(s)

Patent OwnerAddress
ENSUIKO SUGAR REFINING CO LTDTOKYO
BIO RESEARCH CORPORATION OF YOKOHAMAYOKOHAMA-SHI KANAGAWA 230
MANDAI TADAKATSU2-1-19-301 KITAGATA OKAYAMA-SHI OKAYAMA 700

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hara, Koji Yokohama, JP 109 519
Hara, Kozo Yokohama, JP 27 161
Mandai, Tadakatsu 1174-371, Tsurajima, Tsurajima-cho, Kurashiki-shi, Okayama-ken, JP 11 50
Mikuni, Katsuhiko Yokohama, JP 12 81
Nakanishi, Katsuyoshi Yokohama, JP 4 5
Okumoto, Hiroshi Okayama-ken, JP 6 27

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