Antibodies which bind granulocyte-macrophane colony-stimulating factor receptor
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United States of America Patent
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Oct 24, 2000
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app pub date -
Jul 16, 1997
filing date -
Aug 11, 1989
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Abstract
The invention provides a recombinant or synthetic receptor or a derivative thereof, for granulocyte-macrophage colony-stimulating factor (GM-CSF). The GM-CSF receptor is useful, inter alia, in the treatment or diagnosis of GM-CSF-related diseases, and in the screening of agonists and antagonists of GM-CSF receptors. The invention further provides antibodies directed against GM-CSF receptor or derivatives thereof, and pharmaceutical compositions comprising either the GM-CSF receptor, the receptor derivative, or an antibody thereto, and methods of using thereof.
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