Carbohydrate mimetics having antiadhesive properties
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United States of America Patent
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Oct 24, 2000
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N/A
app pub date -
Jul 28, 1997
filing date -
Mar 11, 1994
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Expired
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Abstract
The invention relates to carbohydrate mimetics, which inhibit the binding of selectin to carbohydrate ligands, of the formula I ##STR1## excluding the compounds sialyl-Lewis-X and -A and their derivatives which, instead of an N-acetyl group, carry the substituents N.sub.3, NH.sub.2 or OH or which, instead of fucose, carry glycerol, and pharmaceutical compositions and diagnostic agents containing these derivatives, and methods for using these pharmaceutical compositions and diagnostic agents.
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