Pharmaceutical preparation containing cyclosporin(S) for oral administration and process for producing the said preparation
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United States of America Patent
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Oct 24, 2000
Grant Date -
N/A
app pub date -
Sep 14, 1998
filing date -
Oct 4, 1995
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Abstract
Cyclosporin(s) are formulated as a pharmaceutical preparation that provides good and uniform resorption of the cyclosporin(s) with no nonphysiological pharmaceutical adjuvants, by combining the cyclosporin(s) with (i) monoglycerides, diglycerides, and/or triglycerides of natural fatty acids, (ii) natural fatty acids and/or alkaline salts of natural fatty acids, and (iii) 3-sn-phosphatidyl choline(s), and/or phosphatidyl ethanolamine(s), and optionally also (iv) natural bile acids and/or alkaline salts of natural bile acids, and (v) a natural alcohol. The pharmaceutical preparation does not contain water and is not an emulsion.
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