Sustained release heterodisperse hydrogel systems for insoluble drugs

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United States of America Patent

PATENT NO 6136343
SERIAL NO

09207298

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Abstract

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A sustained release pharmaceutical formulation includes a sustained release excipient including a gelling agent, an inert pharmaceutical diluent, an optional cationic cross-linking agent, and a medicament having moderate to poor solubility is disclosed. In certain embodiments, the sustained release excipient is granulated with a solution or suspension of a hydrophobic polymer in an amount effective to slow the hydration of the gelling agent when the formulation is exposed to an environmental fluid. In another embodiment, the tablet is coated with a hydrophobic polymer.

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Patent Owner(s)

Patent OwnerAddress
EDWARD MENDELL CO INC2981 ROUTE 22 PATTERSON NY 12563-9970

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baichwal, Anand R Wappinger Falls, NY 70 2087

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