Nucleotide sequences that encode phosphatidylinositol-3' kinase associated proteins and uses thereof
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United States of America Patent
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Oct 17, 2000
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app pub date -
Oct 1, 1997
filing date -
Nov 1, 1996
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Abstract
Identification, characterization and expression of nucleotides that encode phosphatidylinositol-3' kinase associated protein(s) that bind to the intermediate SH2 domain on the regulatory subunit of PI3K, p85, by the associated protein(s) C-terminal amino acids, and that exhibit a bromodomain are described, as well as methods of using such proteins for medical applications, including diagnosis and treatment cell growth disorders.
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