Liposomal-viral DNA complexes for treating disease
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United States of America Patent
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Oct 17, 2000
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app pub date -
Feb 22, 1996
filing date -
Feb 22, 1996
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Abstract
Methods and compositions for treating cancer consisting of viral DNA in association with liposomal material, the viral DNA substantially incapable of encoding a functional viral oncoprotein capable of binding to a functional tumor suppressor gene product in a neoplastic cell, and the viral DNA capable of replicating and forming infectious virus in neoplastic cells thereby killing the neoplastic cells and substantially incapable of replicating and forming infectious virus in non-neoplastic cells that have the tumor suppressor protein.
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