Method to regulate CD40 signaling

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United States of America Patent

PATENT NO 6132978
SERIAL NO

08769747

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Abstract

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The present invention relates to methods useful for identifying compounds capable of specifically controlling CD40 regulation of JNK or p38 activity useful for inhibiting immunoglobulin heavy chain class switching, cytokine production and activation of cells involved in an inflammatory response. The present invention also includes kits to perform such assays and methods to control disease related to such responses.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL JEWISH CENTER FOR IMMUNOLOGY AND RESPIRATORY MEDICINE1400 JACKSON STREET DENVER CO 80206

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gelfand, Erwin W Englewood, CO 30 325
Johnson, Gary L Boulder, CO 51 657

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