Immunogenic compositions comprising porphyromonas gingivalis proteins and/or peptides and methods
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United States of America Patent
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Oct 10, 2000
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N/A
app pub date -
Mar 21, 1997
filing date -
Mar 22, 1996
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Expired
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Abstract
Provided herein are methods and immunogenic compositions useful for protecting mammals from infection and pathology of P. gingivalis. Specifically, arginine-specific proteases of Porphyromonas gingivalis and peptides derived therefrom offer protection against infection. Immunogenic compositions comprising a 50 kDa arginine-specific protease, the high molecular weight complex or peptides from one of the foregoing proteins are capable of protecting against P. gingivalis infection and/or gingivitis and/or periodontitis caused thereby in mammals, including humans.
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