Structural alignment method making use of a double dynamic programming algorithm
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United States of America Patent
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Sep 26, 2000
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N/A
app pub date -
Dec 17, 1997
filing date -
Dec 20, 1996
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Expired
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Abstract
There is disclosed a structural alignment method making use of a double dynamic programming algorithm. A distance cut-off approximation is performed, and then .DELTA.N cut-off approximation is performed. An alignment is produced based on the results of the distance cut-off approximation and the .DELTA.N cut-off approximation. Subsequently, an .epsilon.-suboptimal region defined by the obtained approximate solution is determined. Further, double dynamic programing alignment on the full structural environment is performed for residue pairs within the .epsilon.-suboptimal region. The structural alignment method is simpler than conventional methods and can shorten computational time while maintaining high accuracy.
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