Isolated human cytomegalovirus polypeptides and uses thereof
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United States of America Patent
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Sep 19, 2000
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N/A
app pub date -
Jul 25, 1995
filing date -
Jul 26, 1994
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Expired
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Abstract
Diagnostically relevant polypeptides and fusion proteins comprising an amino acid sequence which originates from cytomegalovirus and corresponds to a region of the major DNA-binding protein or of the C-terminal region of the tegument protein pp150 fused with at least one further fragment from another antigenic protein of cytomegalovirus are disclosed. The major DNA-binding protein is encoded by the reading frame UL57. The poly-peptides and fusion proteins according to the invention can be used in an advantageous manner in diagnostic tests and methods for the detection of IgM antibodies against cytomegalovirus.
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