CS-1 peptidomimetics, compositions and methods of using the same
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United States of America Patent
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Sep 12, 2000
Issued Date -
N/A
app pub date -
Apr 14, 1997
filing date -
Dec 6, 1993
priority date (Note) -
Expired
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Abstract
The present invention contemplates a peptide that inhibits the binding between the VLA-4 receptor expressed on inflammatory leukocytes and the fibronectin CS-1 peptide expressed on endothelial cells that are involved in immunoinflammatory disease states. Pharmaceutical compositions containing a contemplated peptide and processes for treating immunoinflammatory conditions using a binding-inhibitory peptide are also disclosed.
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