Anti-Fas ligand antibody and assay method using the anti-Fas ligand antibody

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United States of America Patent

PATENT NO 6114507
SERIAL NO

08649100

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Abstract

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An anti-Fas ligand antibody capable of suppressing Fas ligand-induced apoptosis to a high degree, especially humanized antibodies having less antigenecity to human, and a method for assaying the Fas ligand in human body fluid utilizing such an antibody. Measurement of the Fas ligand in human body fluid would be useful for elucidation of hepatitis B, hepatitis C, HIV infections and the like, and for prediction and diagnosis of pathological conditions associated with such diseases.

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Patent Owner(s)

Patent OwnerAddress
MOCHIDA PHARMACEUTICAL CO LTDTOKYO 160-8515
OSAKA BIOSCIENCE INSTITUTESUITA-SHI OSAKA 565-0874

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Co, Man Sung Cupertino, CA 25 3231
Matsusue, Tomokazu Tokyo, JP 8 122
Nagata, Shigekazu Osaka-fu, JP 26 249
Shirakawa, Kamon Tokyo, JP 34 305
Vasquez, Maximiliano Palo Alto, CA 92 2096

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