Method and apparatus for optically determining total hemoglobin concentration
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United States of America Patent
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Aug 15, 2000
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app pub date -
Feb 27, 1998
filing date -
Jul 12, 1996
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Abstract
In a method of optically determining the total hemoglobin concentration (tHb) in non-hemolyzed whole blood, using at least two wavelengths for measuring, a first wavelength of .lambda.<805 nm and a second wavelength of .lambda.>805 nm is employed, such that the following is valid for the absorption coefficients of the hemoglobin derivatives O.sub.2 Hb and RHb at the two measurement wavelengths .lambda..sub.1 and .lambda..sub.2 : .sigma.O(.lambda..sub.1).about..sigma.R(.lambda..sub.2) and .sigma.R(.lambda..sub.1).about..sigma.O(.lambda..sub.2). The sum of absorption values A.sub.1 and A.sub.2 measured at wavelengths .lambda..sub.1 and .lambda..sub.2 will be a quantity which is proportional to the total hemoglobin concentration tHb and independent of the oxygen saturation O.sub.2sat.
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