Nisins
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United States of America Patent
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-
Aug 8, 2000
Issued Date -
N/A
app pub date -
Dec 24, 1996
filing date -
Apr 2, 1992
priority date (Note) -
Expired
status (Latency Note)
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Abstract
An organism which does not express its natural nisA gene product, but is capable of expressing genes for nisin modification, immunity and translocation out of the cell. The organism may be transformed with a coding sequence for a variant prenisin and appropriate regulatory sequences for expression thereof such that the organism is capable of secreting the corresponding variant nisin. A process for exclusively producing a variant nisin comprises fermenting this organism and obtaining the nisin so produced.
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