Microorganism, lactamase enzyme obtained therefrom, and their use
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United States of America Patent
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Jul 18, 2000
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N/A
app pub date -
Sep 3, 1997
filing date -
Sep 3, 1996
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Expired
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Abstract
A lactamase enzyme having good stability, capable of hydrolysing an enatiomer of the bicyclic lactam, 2-azabicyclo[2.2.1]hept-5-en-3-one, to give (-) lactam and (+) amino acid, has been found in a strain of Comamonas acidivorans. The enzyme has been isolated and cloned, and its structure identified.
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