Device and method for analyzing tumor cell invasion of an extracellular matrix

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United States of America Patent

PATENT NO 6087157
SERIAL NO

08718350

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Abstract

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A device for analyzing the in-vitro growth properties of cells is disclosed. The device comprises an upper and lower chamber separated by a growth substrate interface comprising submucosa, preferably tunical submucosa, from a warm-blooded vertebrae. Methods for culturing eukaryotic cells and studying their growth characteristics, including the invasive growth characteristics of tumor cells, on the submucosal matrix are described.

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Patent Owner(s)

Patent OwnerAddress
PURDUE RESEARCH FOUNDATION101 FOUNDRY DRIVE SUITE 2500 THE CONVERGENCE CENTER WEST LAFAYETTE IN 47906

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Badylak, Stephen F West Lafayette, IN 114 10909
Boder, George Martinsville, IN 3 441
Critser, John K Carmel, IN 19 227
Demeter, Robert J Mooresville, IN 12 1882
Liu, Chi Indianapolis, IN 33 536
Voytik-Harbin, Sherry L Lafayette, IN 29 852

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