Membrane anchor/active compound conjugate, its preparation and its uses

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United States of America Patent

PATENT NO 6074650
SERIAL NO

08465709

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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According to certain embodiments, the invention relates to an immunoconjugate produced by conjugating at least one membrane-anchoring compound with at least one partial sequence of a protein of a virus, a bacterium, a parasite or a tumor antigen. The immunoconjugate has the advantage that it can be stored for a very long time even without cooling. According to certain embodiments, the invention relates to an immunogenic composition for the specific induction of cytotoxic T-lymphocytes which comprises a conjugate from at least one membrane anchor compound and a protein, containing at least one killer T-cell epitope, of a virus, a bacterium, a parasite or a tumor antigen, or at least one partial sequence containing at least one killer T-cell epitope of a viral, bacterial or parasite protein or of a tumor antigen.

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Patent Owner(s)

Patent OwnerAddress
EMC MICROCOLLECTIONS GMBH72070 TÜBINGEN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Deres, Karl Tubingen, DE 5 79
Jung, Gunther Tubingen, DE 14 100
Rammensee, Hans-Georg Tubingen, DE 98 728
Schild, Hansjorg Dornburg, DE 2 9
Wiesmuller, Karl-Heinz Tubingen, DE 7 53

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