Method for simultaneous detection of multiple fluorophores for in situ hybridization and multicolor chromosome painting and banding
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United States of America Patent
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May 23, 2000
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Jun 19, 1998
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Aug 18, 1993
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Abstract
A spectral imaging method for simultaneous detection of multiple fluorophores aimed at detecting and analyzing fluorescent in situ hybridizations employing numerous chromosome paints and/or loci specific probes each labeled with a different fluorophore or a combination of fluorophores for color karyotyping, and at multicolor chromosome banding, wherein each chromosome acquires a specifying banding pattern, which pattern is established using groups of chromosome fragments labeled with various fluorophore or combinations of fluorophores.
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