Non-invasive measurement of blood glucose using instruments that have less precise detection capability
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United States of America Patent
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May 16, 2000
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app pub date -
May 6, 1998
filing date -
May 6, 1998
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Abstract
A method and apparatus are disclosed for improving an accuracy characteristic of a quantitative measurement instrument for measuring a blood analyte concentration by using lower precision sensor devices. One embodiment of the method includes calculating a correction factor based on an elapsed time from a last meal and a substantially typical rise and fall pattern of blood analyte concentrations in the bloodstream. The correction factor is part of a regression analysis equation employed by the blood analyte measurement instrument. A second embodiment includes a method whereby a series of indicator variables are allocated based on the elapsed time from a last meal, and uses the indicator variables in a regression analysis equation. An apparatus having an introducer means for introducing an energy into blood present in a body part of a subject, a detector for detecting the energy emerging from the body part, with the detector producing an electrical signal indicative of the emerging energy, an input element for entering a time from a last meal of the subject, a storage element for storing a regression equation and a correction factor, and a processor for using the regression equation and the correction factor to yield a predicted value of the blood analyte concentration.
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