Quinoline sulfide derivatives
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United States of America Patent
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May 2, 2000
Grant Date -
N/A
app pub date -
Feb 1, 1999
filing date -
Jul 30, 1996
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Expired
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Abstract
The present invention is directed to quinoline sulfide derivatives with antibacterial activities selectively against Hp, obtained by reacting quinoline-4(1H)-thione derivatives with halides and represented by the formula I ##STR1## wherein R.sub.1 represents hydrogen or halogen atom, C.sub.1 -C.sub.6 alkoxy, C.sub.1 -C.sub.6 alkylthio or di C.sub.1 -C.sub.6 alkylamino; R.sub.2 and R.sub.3 respectively represent hydrogen atom or C.sub.1 -C.sub.6 alkyl; one of R.sub.4 and R.sub.5 represents hydroxyl group and the other represents hydrogen atom or CR.sub.4 R.sub.5 represents carbonyl; and m and n are integers, m being 1 or 2, n being 0 or 1.
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