Once-a-day controlled release sulfonylurea formulation
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United States of America Patent
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May 2, 2000
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N/A
app pub date -
Oct 15, 1997
filing date -
Oct 15, 1997
priority date (Note) -
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Abstract
This invention is directed to a novel solid matrixed controlled release, oral dosage form where the dosage form contains a therapeutically effective amount of a sulfonylurea or a salt or derivative thereof in the matrix. Further, the use of an aqueous alkalizing medium affords substantially complete bioavailability of the drug from the matrix of the tablet. The core tablets may optionally be coated with a coating material in the range of 2% to 10% with an enteric material or with a water insoluble material like ethyl cellulose.
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