Transparent aqueous solution of diclofenac sodium and medicinal compositions with the use of the same
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United States of America Patent
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Apr 25, 2000
Grant Date -
N/A
app pub date -
Aug 7, 1998
filing date -
Feb 7, 1996
priority date (Note) -
Expired
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Abstract
Disclosed are a clear aqueous solution of diclofenac sodium dissolved in a mixed solvent of a fatty acid dialkylolamide and water; an anti-inflammatory analgesic composition excellent in percutaneous absorption, which comprises the clear aqueous solution and a higher unsaturated aliphatic alcohol contained in the solution; and a self-adhesive cataplasm comprising a cataplasm base and the clear aqueous solution, polybutene and gelatin added in the base. The clear aqueous solution of diclofenac sodium contains, in particular, diclofenac sodium, a fatty acid dialkylolamide and water at a ratio falling within a hexagonal region formed by linking the points A, B, C, D, E and F in the figure.
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