BRK protein tyrosine kinase and encoding nucleic acid

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United States of America Patent

PATENT NO 6051221
SERIAL NO

08591474

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Abstract

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The invention relates to a novel tyrosine kinase designated brk and the use of this tyrosine kinase in the development of diagnostic and therapeutic approaches to cancer. The novel tyrosine kinase was isolated from a human metastatic breast tumor using a PCR based differential screening approach and has the deduced amino acid sequence shown in SEQ ID NO:2.

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Patent Owner(s)

Patent OwnerAddress
GUSTERSON BARRYDEPARTMENT OF PATHOLOGY WESTERN INFIRMARY GLASGOW G11 6NT

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barker, Karen Tracey Sutton, GB 1 0
Crompton, Mark Roger London, GB 1 0
Gusterson, Barry Austin Greater London, GB 1 0
Kamalati, Taherah London, GB 1 0
Mitchell, Philip John Sutton, GB 7 164
Page, Martin John Biggin Hill, GB 8 152
Spence, Paul Newtown, PA 29 2095

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