Supernucleophilic 4-substituted-pyridine catalysts, and processes useful for preparing same

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United States of America Patent

PATENT NO 6046336
SERIAL NO

09127542

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Abstract

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Described are preferred processes for producing extrusion-granulated supernucleophilic 4-amino-substituted pyridine catalysts, and granular products obtainable therefrom. Also described are preferred activation-substitution-deactivation processes for producing 4-aminopyridine compounds, which involve the use of acrylic acid or acrylamide or analogs thereof for activation, and substitution steps conducted under mild basic conditions in an excess of the amine reagent for 4-substitution. Such processes provide improved reacted masses which are more readily processed to recover the products in pure, heat-stable form. Further, described are processes for preparing 4-substituted-pyridines via pyridine betaines.

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Patent OwnerAddress
WILMINGTON TRUST NATIONAL ASSOCIATION AS COLLATERAL AGENT246 GOOSE LANE SUITE 105 GUILFORD CT 06437

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Balasubramanian, Marudai Indianapolis, IN 4 0
Calvin, Joel R Carmel, IN 6 12
Curtis, Joe W Plainfield, IN 4 0
Hopper, Charles R Plainfield, IN 5 0
Huckstep, L Mark Danville, IN 6 2
Murugan, Ramiah Indianapolis, IN 21 40
Scriven, Eric F V Greenwood, IN 25 72

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