Importance

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Abstract

A polysulfone hollow fiber membrane for blood purification which has no danger that any component of the membrane dissolves out, and which can be used suitably or hemodialysis and blood filtration and remove selectively and efficiently low-molecular-weight proteins having molecular weight of 10,000 to 30,000 contained in blood, as well as a blood purifier which can be used suitably as a hemodialyzer, a filter for hemodiafiltration and a blood filter are provided. The hollow fiber membrane comprises a polysulfone resin, wherein there are slit-shaped micropores having an average width of 0.02 to 0.15 .mu.m on the inner surface thereof; there are micropores having an average pore size of 0.1 to 1 .mu.m on the outer surface thereof; the inside thereof has a sponge-like structure; there are no large voids having a diameter of more than 10 .mu.m on the inner and outer surface thereof and inside the membrane; water permeability thereof is 400 to 2,500 ml/m.sup.2 .multidot.hr.multidot.mmHg; and a permeation rato for the total proteins is 1% or less. The blood puifier contains the hollow fiber membrane put into a cylindrical housing which is equipped with a blood inlet and a blood outlet, and either a dialysate solution inlet and a dialysate solution outlet or a filtrate outlet.

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First Claim