3-amino-2-oxo-1-piperidnercetic derivatives as enzyme inhibitors

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United States of America Patent

PATENT NO 6034215
SERIAL NO

08950270

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Abstract

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The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.

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Patent Owner(s)

Patent OwnerAddress
DENDREON PHARMACEUTICALS INC400 SOMERSET CORPORATE BOULEVARD BRIDGEWATER NJ 08807

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ardecky, Robert John Encinitas, CA 11 154
Brunck, Terence Kevin San Diego, CA 5 55
Lim-Wilby, Marguerita S L La Jolla, CA 4 60
Nutt, Ruth Foelsche San Diego, CA 8 75
Ripka, William Charles San Diego, CA 16 285
Rowley, David C Encinitas, CA 6 46
Semple, Joseph Edward San Diego, CA 25 382

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