Method for preparing the fimbrin protein of Haemophilus influenzae
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United States of America Patent
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Feb 29, 2000
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N/A
app pub date -
Jun 6, 1995
filing date -
May 18, 1993
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Abstract
It has been discovered that a vaccine comprised of fimbrin, a filamentous protein derived from the bacterial surface appendages of non-typable Haemophilus influenzae is useful in studying, preventing or reducing the severity of, otitis media. The gene sequence of the DNA coding for fimbrin and the amino acid sequence of fimbrin have also been determined. Vectors containing DNA coding for fimbrin have also been developed, and transformants have been prepared which contain such vectors and which express such DNA and provide a source of pure fimbrin.
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