Diazaspiro, azepino and azabicyclo therapeutic peptides

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United States of America Patent

PATENT NO 6025471
SERIAL NO

09089954

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Abstract

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The present invention relates a number of novel peptide sequences which include a spirolactam, bicyclic or tricyclic peptidomimetic unit. The peptides disclosed herein exhibit binding to cardiac tissue and normalize cardiac pressure after administration, as well as diagnostic and therapeutic properties for certain neoplastic tissues. Importantly, these peptides do not release pituitary hormones such as corticotropin (ACTH) and growth hormone (GH), and are therefore devoid of certain unwanted side-effects. These peptides preferably have at least one lysine unit and at least one D-2-alkyl-trptophan unit.

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Patent Owner(s)

Patent OwnerAddress
ARDANA BIOSCIENCE LIMITED58 QUEEN STREET ENDINBURGH EH2 3NS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Deghenghi, Romano Chesaux-Dessus, St. Cergue, CH 32 724

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