Template associated NPY Y2-receptor agonists
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United States of America Patent
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Jan 25, 2000
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N/A
app pub date -
Apr 3, 1998
filing date -
Apr 3, 1998
priority date (Note) -
Expired
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Abstract
The present invention is directed to agonists of neuropeptide Y (NPY) or PYY that are formed by combining these peptides or a portion of these peptides with a template that promotes biologically active folds. Typically, templates consist of cyclized peptides containing one or more naphthyl ring structures. The agonists may be used in the treatment of diseases and conditions known to be responsive to NPY or PYY and, particularly in the treatment of asthma, rhinitis, and bronchitis.
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