Process for the preparation of enantiomerically pure 3-hydroxyoctanedioic acid diesters by asymmetric catalytic hydrogenation
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United States of America Patent
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Jan 11, 2000
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N/A
app pub date -
Mar 6, 1998
filing date -
Mar 6, 1997
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Expired
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Abstract
The invention relates to a process for the preparation of compounds of the general formula I ##STR1## in which R.sup.1 and R.sup.2 are identical or different and are a C.sub.1 -C.sub.20 -alkyl group, C.sub.3 -C.sub.12 -cycloalkyl group, C.sub.7 -C.sub.12 -aralkyl group or a mono- or binuclear aryl group, in which a ketone of the formula III or IV ##STR2## in which R.sup.1 and R.sup.2 have the above meaning, is asymmetrically hydrogenated.
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