Process for the preparation of azithromycin
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United States of America Patent
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Jan 11, 2000
Grant Date -
N/A
app pub date -
May 18, 1998
filing date -
May 19, 1997
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention describes a new process for the preparation of azithromycin from a suitable imino ether as precursor, characterised by the fact that the reduction and the reductive methylation of said imino ether are sequentially carried out with a noble metal catalyst and hydrogen in the presence of formaldehyde, or a source thereof, wherein both reactions can be conducted in the same reaction vessel.
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