Fused cell line and method of obtaining the same

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United States of America Patent

PATENT NO 6013518
SERIAL NO

09001995

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Abstract

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Provided are a human immunocompetent fused cell line, characterized in that any one of a mutant cell selected from the group consisting of ICLU-B, ICLU-T and ICLU-E is used as a parent cell line, wherein said mutant cell is obtained by selecting an 8-azaguanine- or 6-thioguanine-resistant clone from a human Burkitt lymphoma cell line Raji, a human T-cell lymphocytic leukemia cell line PEER and a human eosinophilic leukemia cell line EoL-1, and then treating said clone in order to capable of serum-free culture, and a method of obtaining said human immunocompetent fused cell line. The human immunocoipetent fused cell line obtained by the present invention is used to investigate food functions, novel drugs and production thereof with the view to the elucidation of mechanisms of phenomena of an immune system such as allergies, cancers and the like using human cell lines, and the prevention, diagnosis and therapy of these diseases.

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Patent Owner(s)

Patent OwnerAddress
BIO ORIENTED TECHNOLOGY RESEARCH ADVANCEMENT INSTITUTION40-2 NISSHINCHO 1-CHOME OMIYA-SHI SAITAMA-KEN 331
DIRECTOR-GENERAL OF NATIONAL RESEARCH INSTITUTE OF VEGETABLES ORNAMENTAL PLANTS AND TEA MINISTRY OF AGRICULTURE FORESTRY AND FISHERIES360 OAZA KUSAWA ANO-CHO AGE-GUN MIE-KEN 514-2392

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kawahara, Hiroharu Shimada, JP 6 11
Osada, Kazuhiro Shimada, JP 5 16
Tsuji, Kenkou Shizuoka-ken, JP 4 7
Yamamoto, Mari Kakegawa, JP 35 263

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