Preparation of noroxymorphone from morphine
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United States of America Patent
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Dec 28, 1999
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N/A
app pub date -
Jul 16, 1998
filing date -
Jul 26, 1996
priority date (Note) -
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Abstract
The invention provides processes for the conversion of normorphinone and its derivatives, which can be synthesized from morphine, to the corresponding 14-hydroxynormorphinone and its derivatives including oxycodone, oxymorphone, noroxymorphone and naltrexone. Noroxymorphone is a key intermediate for the production of important narcotic analgesics and antagonists. The invention also provides certain novel intermediates.
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