Aromatic hetherocyclic derivatives as enzyme inhibitors
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United States of America Patent
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Dec 28, 1999
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app pub date -
Dec 18, 1995
filing date -
Dec 13, 1994
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Abstract
The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.
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