Use of von willebrand factor and pharmaceutical formulation
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United States of America Patent
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Dec 21, 1999
Grant Date -
N/A
app pub date -
Nov 6, 1996
filing date -
Nov 10, 1995
priority date (Note) -
Expired
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Abstract
The invention relates to the use of von Willebrand Factor (vWF) with a prolonged biological half-life for the production of a preparation for stabilization of blood coagulation Factor VIII (FVIII:C) in a mammal. Additionally, a pharmaceutical preparation is provided comprising a biologically active FVIII:C/vWF complex with improved pharmokinetic properties, said complex containing a vWF with a prolonged biological half-life.
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